A dose that is lethal to 50% of the population is known as

A dose that is lethal to 50% of the population is known as

• A. LC50
• B. TD50
• C. ED50
• D. LD50

Answer: (D)

LD50 denotes the dose of a substance expected to cause death in 50% of a test population, typically expressed as an amount per body weight (e.g., mg/kg). It’s a standard measure of acute toxicity used to compare how toxic different substances are. This differs from LC50, which uses lethal concentration in air for inhalation exposures; ED50, which is the dose that produces the desired therapeutic effect in 50% of the population; and TD50, which is the dose that causes a specified toxic effect (not necessarily death) in 50%. Since the question asks for the dose that is lethal to half the population, the appropriate term is LD50.

LD50 denotes the dose of a substance expected to cause death in 50% of a test population, typically expressed as an amount per body weight (e.g., mg/kg). It’s a standard measure of acute toxicity used to compare how toxic different substances are. This differs from LC50, which uses lethal concentration in air for inhalation exposures; ED50, which is the dose that produces the desired therapeutic effect in 50% of the population; and TD50, which is the dose that causes a specified toxic effect (not necessarily death) in 50%. Since the question asks for the dose that is lethal to half the population, the appropriate term is LD50.